One of aspects of the carpets which can be studied is their pattern and design, and such a study can be performed based on theoretical and scientific-artistic approaches, including symbol and sign. In fact, by studying and analyzing designs and patterns of carpets on the basis of a semiotic system, semantic signification of them can be analyzed. Accordingly, a carpet with corner-medallion pattern as well as a pictorial carpet among carpets of Hamedan is studied here. Hamedan is one of the most important areas of carpet-weaving, especially in terms of rural style. Pictorial and corner-medallion designs were selected for better manifestation of the differences between symbol and sign, since there are occasionally considered to be identical that and sometimes to be different. Based on what was said, the research question is that "Can the differences symbol and sign be studied in the pattern carpets and to obtain semantic significations in the contest of semiotics? Accordingly analytical and comparative methods as well as desk study method for data collection have been employed. First the theoretical bases of the research have been reviewed and then the selected samples have been studied regarding such theoretical criteria. The results of this research include: understanding the differences between symbols and signs in pattern of hand-made carpets, the effectiveness of semiotic system in the process of analysis of such symbols and signs as well as achieving semantic implications of patterns through conceptual abundance, based on semiotics method.